Bacillus coagulans

Bacillus coagulans BCP92 (MTCC25460)

Bacillus coagulans recently renamed as Heyndrickxia coagulans1 is gram positive, spore forming, non-pathogenic, non hemolytic2, rod shaped bacterium, stable at wide range of pH and temperature. Produces lactic acid and bacteriocins which prevent the growth of pathogenic microorganism. It can sustain gastric and bile acids in human gut and remains stable in highly acidic environment. Approved as GRAS3 in US and QPS4 status in EU.

Benefits

  1. USFDA GRAS approved strain safe for human consumption3
  2. It helps overall gut health.
  3. Highly thermal stability does not require refrigeration
  4. Survives gastric acid barrier
  5. Clinically proven strain5
  6. Proven application in various food matrix6

Application

Foods
B. coagulans BCP92 can be used in a range of functional foods and bevarages, such as ice and hot tea, juices, instant coffee, flavored drink, sports drink, yogurt, cereal bars breakfast cereals, and ice creams, chocolates, ready mix soup, instant noodles, ketchup, etc.
B. coagulans BCP92 can be used in a variety of baked goods such as sandwich bread, muffin, brownies, cakes, cookies, pizza etc.

Nutraceuticals
B. coagulans BCP92 can also be used in various dosage form such as tablet, capsule, oral suspension, gummies, sachets in nutraceutical application.

Features

  1. Spray dried Product Bacillus coagulans is manufactured in FSSC 22000 certified GMP manufacturing facility.
  2. Manufactured using no animal origin components and is Kosher and Halal certified.
  3. Stable through a wide range of pH and temperature.
  4. Resistant to bile salt.
  5. Stable in beverages such as tea, coffee, gummies and energy drinks.
  6. Stable in baked goods and energy bars.
  7. Allergen-Free

Availability & Packaging

  1. Bulk powder available in potency of 200, 150 Billion CFU/g.
  2. Blended product available in potency of 100, 50, 25, 15, 6 Billion CFU/g.
  3. Packaging in Double Polyethylene liners in HDPE Drums or foil bags.
  4. Foil Bags: 25 kgs, 20 kgs, 10 kgs, 5kgs, 1Kg in foil bags
  5. Drum: 25 kgs and 20 kgs.

Documents

  1. Microbial Identification Report – 16S rRNA
  2. Whole Genome Sequence Report
  3. Certificate of Analysis (COA)
  4. Material Safety Data Sheet (MSDS)
  5. Stability Data

References​

  1. “Genome-based reclassification of Bacillus acidicola, Bacillus pervagus and the genera Heyndrickxia, Margalitia and Weizmannia.” Int. J. Syst. Evol. Microbiol. (2023) 73(7):005961.
  2. In-silico analysis of probiotic attributes and safety assessment of probiotic strain Bacillus coagulans BCP92 for human application, Letters in Applied Microbiology, Volume 77, Issue 1, January 2024, ovad145, https://doi.org/10.1093/lambio/ovad145
  3. USFDA GRAS GRN# 1159 https://www.cfsanappsexternal.fda.gov/scripts/fdcc/?set=GRASNotices
  4. Introduction of a Qualified Presumption of Safety (QPS) approach for assessment of selected microorganisms referred to EFSA. The EFSA Journal (2007) 587, 1-16
  5. Role of Bacillus coagulans (Heyndrickxia coagulans) BCP92 in Managing Irritable Bowel Syndrome: A Randomized, Double-Blind, multicentre, Placebo-Controlled Clinical Trial. Medicine 103(31):p e39134 | DOI:10.1097/MD.0000000000039134
  6. Food storage, processing and genetic stability studies of B. coagulans BCP92 (MTCC 25460). Applied Food Biotechnology, 11(1), e22. https://doi.org/10.22037/afb.v11i1.44919.

Certificate

Licences and Certificates

fssai-lic
koshar
eurofin
Gmf-Food-Product
Sedex2
fsssc
halal